Preimplantation genetic analysis

J Reprod Med. 1992 May;37(5):428-36.


Advanced reproductive technologies have afforded us access to human preembryos, allowing the possibility of preimplantation genetic diagnosis of certain genetic diseases. This paper thoroughly reviews both the micro-manipulation and molecular biologic aspects of this new and exciting branch of medicine. In addition, some of the moral and ethical considerations relating to preembryo genetic diagnosis are discussed.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Biopsy
  • Cryopreservation / methods
  • Cryopreservation / standards
  • DNA
  • Embryonic Development*
  • Ethics, Medical
  • Female
  • Fertilization in Vitro*
  • Genetic Testing / methods*
  • Genetic Testing / standards
  • Humans
  • Nucleic Acid Hybridization
  • Oligonucleotide Probes
  • Polymerase Chain Reaction
  • Pregnancy


  • Oligonucleotide Probes
  • DNA