Identification of genes dependent on the MADS box transcription factor SrfA in Dictyostelium discoideum development

Eukaryot Cell. 2004 Apr;3(2):564-6. doi: 10.1128/EC.3.2.564-566.2004.

Abstract

Analysis of microarrays containing 6,345 Dictyostelium discoideum genes has identified 21 whose expression is dependent on the MADS box transcription factor SrfA. In wild-type cells, all of these genes are induced late in development. At least four of them are necessary for proper spore differentiation, stability, and/or germination.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Dictyostelium / genetics*
  • Dictyostelium / growth & development*
  • Gene Expression Regulation, Developmental
  • Gene Silencing
  • Genes, Protozoan / genetics*
  • MADS Domain Proteins / genetics
  • MADS Domain Proteins / physiology*
  • Oligonucleotide Array Sequence Analysis
  • Protozoan Proteins / genetics
  • Transcription Factors / genetics
  • Transcription Factors / physiology*

Substances

  • MADS Domain Proteins
  • Protozoan Proteins
  • Transcription Factors