Abstract
Analysis of microarrays containing 6,345 Dictyostelium discoideum genes has identified 21 whose expression is dependent on the MADS box transcription factor SrfA. In wild-type cells, all of these genes are induced late in development. At least four of them are necessary for proper spore differentiation, stability, and/or germination.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Dictyostelium / genetics*
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Dictyostelium / growth & development*
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Gene Expression Regulation, Developmental
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Gene Silencing
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Genes, Protozoan / genetics*
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MADS Domain Proteins / genetics
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MADS Domain Proteins / physiology*
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Oligonucleotide Array Sequence Analysis
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Protozoan Proteins / genetics
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Transcription Factors / genetics
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Transcription Factors / physiology*
Substances
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MADS Domain Proteins
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Protozoan Proteins
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Transcription Factors