Clostridial orthopedic infections: case reports and review of the literature

J Chemother. 2004 Feb;16(1):94-7. doi: 10.1179/joc.2004.16.1.94.


Clostridia are anaerobic Gram-positive bacilli that can be isolated from the soil and the intestinal tract of humans. These microorganisms are recognized as the cause of devastating soft tissue infections, such as cellulitis, myositis, and gas gangrene. However, such bacteria may also be involved in various postoperative orthopedic infections, including prosthetic joint infection. We present three clinical cases of clostridial orthopedic infection and review the related medical literature.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Anti-Bacterial Agents / therapeutic use
  • Child
  • Clostridium Infections / drug therapy
  • Clostridium Infections / etiology*
  • Clostridium Infections / pathology
  • Female
  • Humans
  • Joint Prosthesis / microbiology*
  • Male
  • Orthopedic Procedures / adverse effects*
  • Surgical Wound Infection*
  • Treatment Outcome


  • Anti-Bacterial Agents