Frequency and characteristics of hospital admissions associated with drug-related problems in paediatrics

Br J Clin Pharmacol. 2004 May;57(5):611-5. doi: 10.1111/j.1365-2125.2003.02052.x.


Aim: To determine the frequency of paediatric hospital admissions associated with drug-related problems (DRPs) at two Australian hospitals.

Methods: The investigator and ward pharmacists prospectively screened eligible patients. A multidisciplinary panel reviewed data and established causality, preventability and clinical significance classifications.

Results: Over 22 weeks of data collection, a total of 11,564 patients were admitted, 2933 met eligibility criteria. Of those eligible, 127 [4.3%, 95% confidence interval (CI) 3.6, 5.0] were judged to have hospital admissions associated with DRPs. Direct costs associated with DRPs identified totalled pounds 100,707. Of the 81 cases assessed for preventability, 46.9% were deemed preventable.

Conclusions: This research has provided information on the nature and characteristics of paediatric DRPs associated with hospital admissions.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Australia / epidemiology
  • Child
  • Child, Preschool
  • Costs and Cost Analysis
  • Hospitalization / economics
  • Hospitalization / statistics & numerical data*
  • Humans
  • Infant
  • Infant, Newborn
  • Prospective Studies
  • Substance-Related Disorders / economics
  • Substance-Related Disorders / epidemiology*
  • Substance-Related Disorders / therapy