Severe hypercalcemia in a lactating woman in association with moderate calcium carbonate supplementation: a case report

J Reprod Med. 2004 Mar;49(3):214-7.


Background: Lactation results in dramatic bone resorption and decreased urinary calcium excretion due to rapidly falling estrogen levels and probably increased levels of parathyroid hormone-related protein.

Case: A healthy, 36-year-old woman developed severe hypercalcemia several days after beginning breast-feeding her second child. During and after this pregnancy, she supplemented a high calcium diet with moderate amounts of calcium carbonate in an attempt to avoid an osteoporotic fracture that occurred while she was breast-feeding her first child.

Conclusion: Because the metabolic changes that occur during lactation predispose a woman to hypercalcemia, the daily recommended daily allowances for calcium should not be exceeded during breast-feeding.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Calcium, Dietary / administration & dosage*
  • Calcium, Dietary / adverse effects
  • Diagnosis, Differential
  • Dietary Supplements / adverse effects
  • Female
  • Humans
  • Hypercalcemia / chemically induced
  • Hypercalcemia / diagnosis*
  • Hypercalcemia / pathology
  • Lactation*
  • Puerperal Disorders / chemically induced
  • Puerperal Disorders / diagnosis*
  • Puerperal Disorders / pathology
  • Severity of Illness Index


  • Calcium, Dietary