Distal embolization and local vessel wall ulceration after gastric variceal obliteration with N-butyl-2-cyanoacrylate: a case report and review of the literature

Endoscopy. 2004 May;36(5):442-6. doi: 10.1055/s-2004-814323.


Repeated endoscopic injections of N-butyl-2-cyanoacrylate mixtures into large gastric varices in a single patient led to two complications: initially, pulmonary embolism, and later local ulceration of the wall of a varix. The latter resulted in massive uncontrollable hemorrhage that ultimately led to a fatal outcome. This case report also analyzes complications reported in the literature during similar endoscopic procedures for gastric varices.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Embolization, Therapeutic / adverse effects*
  • Enbucrilate / administration & dosage*
  • Enbucrilate / adverse effects
  • Enbucrilate / analogs & derivatives*
  • Esophageal and Gastric Varices / therapy*
  • Fatal Outcome
  • Female
  • Gastrointestinal Hemorrhage / etiology*
  • Humans
  • Pulmonary Embolism / etiology*
  • Recurrence
  • Retreatment
  • Rupture / chemically induced
  • Tissue Adhesives / administration & dosage*
  • Tissue Adhesives / adverse effects


  • Tissue Adhesives
  • Enbucrilate