Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2004 Feb;25(2):75-84.
doi: 10.1016/

Chemokines: Multiple Levels of Leukocyte Migration Control


Chemokines: Multiple Levels of Leukocyte Migration Control

Bernhard Moser et al. Trends Immunol. .


The surge in interest in chemokines is explained by the recognition that numerous aspects of immunity are intimately related to leukocyte traffic. Chemokines are leukocyte attractants but also contribute to immune processes that do not directly involve leukocyte migration. Recent progress is most evident in the areas of lymphocyte development, immune response initiation and immune pathology. Important observations have also been reported on chemokine-receptor interactions, signal transduction and cellular responses. New insights into the role of chemokines in leukocyte attraction and relocation will be discussed, with emphasis on the distinct levels of leukocyte migration control that ultimately determine the performance of our immune defense system.

Similar articles

See all similar articles

Cited by 193 articles

See all "Cited by" articles

Publication types

LinkOut - more resources