Efficacy of Enicostemma littorale in Type 2 diabetic patients

Phytother Res. 2004 Mar;18(3):233-5. doi: 10.1002/ptr.1434.

Abstract

Pills prepared from Enicostemma littorale (Gentianaceae) were administered to 84 patients with Type 2 Diabetes for three months. Estimation of various biochemical parameters showed that E. littorale reduced blood glucose as well as serum insulin levels and prevented the progression of complications in diabetic patients. Significant improvement in kidney function, lipid profile and blood pressure was observed suggesting that E. littorale is an effective herbal antidiabetic.

Publication types

  • Clinical Trial
  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Blood Glucose / drug effects
  • Blood Glucose / metabolism
  • Blood Pressure / drug effects
  • Cholesterol / blood
  • Cholesterol, HDL / blood
  • Cholesterol, HDL / drug effects
  • Diabetes Mellitus, Type 2 / prevention & control*
  • Female
  • Gentianaceae*
  • Humans
  • Hypoglycemic Agents / administration & dosage
  • Hypoglycemic Agents / pharmacology*
  • Hypoglycemic Agents / therapeutic use
  • India
  • Insulin / blood
  • Kidney / drug effects
  • Kidney / physiology
  • Male
  • Middle Aged
  • Phytotherapy*
  • Plant Extracts / administration & dosage
  • Plant Extracts / pharmacology*
  • Plant Extracts / therapeutic use
  • Triglycerides / blood

Substances

  • Blood Glucose
  • Cholesterol, HDL
  • Hypoglycemic Agents
  • Insulin
  • Plant Extracts
  • Triglycerides
  • Cholesterol