Maternal metabolic phenotype and risk of Down syndrome: beyond genetics

Am J Med Genet A. 2004 May 15;127A(1):1-4. doi: 10.1002/ajmg.a.20648.
No abstract available

MeSH terms

  • Down Syndrome / etiology*
  • Down Syndrome / genetics
  • Female
  • Ferredoxin-NADP Reductase / genetics
  • Ferredoxin-NADP Reductase / metabolism
  • Folic Acid / metabolism
  • Homocysteine / blood
  • Homocysteine / metabolism
  • Humans
  • Maternal Nutritional Physiological Phenomena*
  • Methylenetetrahydrofolate Reductase (NADPH2) / genetics
  • Methylenetetrahydrofolate Reductase (NADPH2) / metabolism
  • Polymorphism, Genetic
  • Pregnancy
  • Risk Factors
  • Vitamin B 12 Deficiency / genetics
  • Vitamin B 12 Deficiency / metabolism

Substances

  • Homocysteine
  • Folic Acid
  • methionine synthase reductase
  • Ferredoxin-NADP Reductase
  • Methylenetetrahydrofolate Reductase (NADPH2)