Macular thickness in patients with choroidal neovascularization determined by RTA and OCT3: comparative results

Eye (Lond). 2005 Jan;19(1):72-6. doi: 10.1038/sj.eye.6701400.


Aims: The authors conducted a study to compare retinal thickness in patients with choroidal neovascularization (CNV) using optical coherence tomography (OCT) and retinal thickness analyser (RTA).

Methods: In all, 11 eyes from 11 patients with subfoveal choroidal neovascularization were examined with OCT and RTA.

Results: Three patients could not be explored by RTA due to lack of fixation and high myopia. The mean foveal thickness was 289.9+/-92.1 microm with OCT and 207.7+/-60.8 microm with RTA. The mean perifoveal thickness was 293.8+/-46.3 microm and 200.8+/-61.3 microm, respectively. The maximal perifoveal thickness measured by OCT was 335+/-104.0 microm and 316+/-86.8 microm by RTA.

Conclusion: OCT and RTA are able to detect increases in retinal thickness due to the presence of CNV and of fluid extravasation. They can be used in measuring retinal thickness in patients with CNV, although measures are not comparable between both systems.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Choroidal Neovascularization / complications
  • Choroidal Neovascularization / pathology*
  • Female
  • Fovea Centralis / pathology
  • Humans
  • Macula Lutea / pathology*
  • Male
  • Middle Aged
  • Myopia / complications
  • Myopia / pathology
  • Tomography, Optical Coherence / methods