[Melanoma of sphenoid sinus. Case presentation and review of literature]

Acta Otorrinolaringol Esp. 2004 Jan;55(1):45-8. doi: 10.1016/s0001-6519(04)78482-4.
[Article in Spanish]


The primary malignant melanomas of sphenoidal sinus are very uncommon tumours. We are reporting a clinical case of a 56 years-old male who was sent from the Neurology Department with ocular pain and headache of several months evolution and without personal history. Exploration revealed a VIth palsy, diplopia and ptosis. The complementary imaging tests (CT and MR) showed and expansive tumour of the sphenoidal sinus involving the right cavenous sinus. A F.E.S.S. with biopsy was performed to confirm the diagnosis. Our patient was treated by Radiotherapy and after a 4 year follow-up period he is still alive. We have carried to a bibliographic review of this pathology whose differential diagnosis must be done with epidermoid carcinomas, adenocarcinomas and lymphomas on that location.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Melanoma / diagnostic imaging*
  • Melanoma / pathology*
  • Melanoma / surgery
  • Middle Aged
  • Paranasal Sinus Neoplasms / diagnostic imaging*
  • Paranasal Sinus Neoplasms / pathology*
  • Paranasal Sinus Neoplasms / surgery
  • Radiography
  • Sphenoid Sinus / diagnostic imaging*
  • Sphenoid Sinus / pathology*
  • Sphenoid Sinus / surgery