[Gene cellular therapy and its potential use in transplantology for preventing transplant rejection]

Biomed Khim. Jan-Feb 2004;50(1):3-24.
[Article in Russian]


Review considers perspectives and the main advantages in the development of the approaches to gene therapy in organ and cell transplantology. The methods of prevention in allo- and xenotransplantation by the inhibition of the recipient immune system, and the problem of specific tolerance to graft in host organism creation by mixed antigenic chimerism making by means of gene therapy methods are discussed.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Animals
  • Gene Transfer Techniques
  • Genetic Therapy*
  • Graft Rejection / immunology
  • Graft Rejection / prevention & control*
  • Humans
  • Organ Transplantation / methods*
  • Transplantation, Heterologous / immunology
  • Transplantation, Homologous / immunology