Left atrium remodeling after acute myocardial infarction (results of the GISSI-3 Echo Substudy)

Am J Cardiol. 2004 May 1;93(9):1156-9. doi: 10.1016/j.amjcard.2004.01.046.


To evaluate the existence, timing, and determinants of post-infarction left atrial remodeling, we studied a subgroup of 514 patients from the Third Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico Echo Substudy who underwent 4 serial 2-dimensional echocardiograms up to 6 months after acute myocardial infarction. This study is the first to demonstrate, in a large series of patients, the existence of early and late left atrial remodeling after low-risk acute myocardial infarction and the relation of left atrial remodeling to left ventricular remodeling.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Echocardiography*
  • Female
  • Follow-Up Studies
  • Heart Atria / diagnostic imaging
  • Heart Atria / physiopathology
  • Heart Ventricles / diagnostic imaging
  • Heart Ventricles / physiopathology
  • Humans
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Myocardial Infarction / diagnostic imaging*
  • Myocardial Infarction / physiopathology*
  • Postoperative Complications / diagnostic imaging*
  • Postoperative Complications / etiology*
  • Postoperative Complications / physiopathology*
  • Severity of Illness Index
  • Statistics as Topic
  • Stroke Volume / physiology
  • Ventricular Remodeling / physiology