Electromagnetic field of extremely low frequency decreased adenylate kinase activity in retinal rod outer segment membranes

Bioelectrochemistry. 2004 Jun;63(1-2):317-20. doi: 10.1016/j.bioelechem.2003.10.029.


Adenylate kinase activity in rod outer segment membranes of bovine retina decreased of about 55% when exposed to an extremely low frequency electromagnetic field of 75 Hz and 250 microT. The effect was independent of the time of permanence in the field. Negligible effects of the field were found on the enzymatic activity of a soluble isoform of adenylate kinase or of rod outer segment membranes solubilized with Triton, suggesting the importance of the membrane in determining the conditions of the enzyme inactivation.

MeSH terms

  • Adenosine Triphosphate / metabolism*
  • Adenylate Kinase / chemistry
  • Adenylate Kinase / metabolism*
  • Adenylate Kinase / radiation effects*
  • Cell Membrane / enzymology*
  • Cell Membrane / radiation effects*
  • Cells, Cultured
  • Dose-Response Relationship, Radiation
  • Electricity
  • Electromagnetic Fields
  • Enzyme Activation / radiation effects
  • Radiation Dosage
  • Retinal Rod Photoreceptor Cells / enzymology*
  • Retinal Rod Photoreceptor Cells / radiation effects*


  • Adenosine Triphosphate
  • Adenylate Kinase