Premenstrual dysphoric disorder: a review for the treating practitioner

Cleve Clin J Med. 2004 Apr;71(4):303-5, 312-3, 317-8 passim. doi: 10.3949/ccjm.71.4.303.

Abstract

Premenstrual dysphoric disorder (PMDD), a severe form of premenstrual syndrome (PMS), is characterized by physical and behavioral symptoms that cause marked social impairment during the last half of the menstrual cycle. Symptoms are believed to result from the interaction of central neurotransmitters and normal menstrual hormonal changes. Treatment usually begins with lifestyle changes, over-the-counter medications, and if needed, selective serotonin reuptake inhibitors. Physicians should be aware of the risks of many of the alternative therapies commonly touted in the popular press.

Publication types

  • Comparative Study
  • Review

MeSH terms

  • Adult
  • Antidepressive Agents / therapeutic use
  • Combined Modality Therapy
  • Dietary Supplements
  • Female
  • Gynecology / methods
  • Humans
  • Ovariectomy / methods
  • Phytotherapy / methods
  • Premenstrual Syndrome / diagnosis*
  • Premenstrual Syndrome / epidemiology
  • Premenstrual Syndrome / therapy*
  • Prognosis
  • Risk Assessment
  • Selective Serotonin Reuptake Inhibitors / therapeutic use
  • Severity of Illness Index
  • Treatment Outcome

Substances

  • Antidepressive Agents
  • Serotonin Uptake Inhibitors