Age-related macular degeneration and depression: a review of recent research

Curr Opin Ophthalmol. 2004 Jun;15(3):181-3. doi: 10.1097/


Purpose of review: The purpose of this review is to summarize current research findings regarding relationships between depression and age-related macular degeneration (AMD).

Recent findings: The current literature indicates that the prevalence of depression among patients with AMD is fairly high (approximately 30%) and that depression is a major cause of disability among patients with AMD, even when severity of vision loss is considered. Interventions to alleviate the emotional distress associated with vision loss are also discussed.

Summary: Several studies indicate that AMD is a risk factor for depression, and this has serious consequences for the quality of life among patients with AMD.

Publication types

  • Review

MeSH terms

  • Biomedical Research / trends
  • Depression / physiopathology
  • Depression / psychology*
  • Humans
  • Macular Degeneration / physiopathology
  • Macular Degeneration / psychology*
  • Risk Factors