[Activation of G-proteins in three dimensions: one step toward the therapeutic inhibition of nucleotide exchange factors]

Med Sci (Paris). 2004 Apr;20(4):393-6. doi: 10.1051/medsci/2004204393.
[Article in French]
No abstract available

Publication types

  • News
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Brefeldin A / pharmacology
  • Drug Design
  • GTP-Binding Proteins / physiology*
  • Guanine Nucleotide Exchange Factors / antagonists & inhibitors*
  • Guanine Nucleotide Exchange Factors / physiology
  • Guanosine Diphosphate / metabolism
  • Guanosine Triphosphate / metabolism
  • Humans
  • Macromolecular Substances
  • Models, Biological
  • Models, Molecular
  • Protein Conformation
  • Signal Transduction / physiology*
  • Structure-Activity Relationship

Substances

  • Guanine Nucleotide Exchange Factors
  • Macromolecular Substances
  • Guanosine Diphosphate
  • Brefeldin A
  • Guanosine Triphosphate
  • GTP-Binding Proteins