Neurofibromatosis in children with Rhabdomyosarcoma: a report from the Intergroup Rhabdomyosarcoma study IV

J Pediatr. 2004 May;144(5):666-8. doi: 10.1016/j.jpeds.2004.02.026.

Abstract

We identified all children enrolled in the Intergroup Rhabdomyosarcoma Study Group-IV with neurofibromatosis type I (NF1) and rhabdomyosarcoma. Among 1025 eligible patients, 5 (0.5 %) had NF1. Three children had relapses, two of whom died of progressive disease. Patients with NF1 and rhabdomyosarcoma should be treated with intensive contemporary therapy protocols.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Canada / epidemiology
  • Child
  • Child, Preschool
  • Disease-Free Survival
  • Female
  • Humans
  • Infant
  • Male
  • Neoplasms, Second Primary / epidemiology*
  • Neoplasms, Second Primary / mortality
  • Neoplasms, Second Primary / pathology
  • Neurofibromatosis 1 / epidemiology*
  • Neurofibromatosis 1 / mortality
  • Neurofibromatosis 1 / pathology
  • Prevalence
  • Prostatic Neoplasms / epidemiology
  • Prostatic Neoplasms / pathology
  • Retrospective Studies
  • Rhabdomyosarcoma / epidemiology
  • Rhabdomyosarcoma / mortality
  • Rhabdomyosarcoma / pathology*
  • Survival Rate
  • Urinary Bladder Neoplasms / epidemiology
  • Urinary Bladder Neoplasms / pathology