A role for bacteria in celiac disease?

Am J Gastroenterol. 2004 May;99(5):905-6. doi: 10.1111/j.1572-0241.2004.04158.x.

Abstract

The finding of rod-shaped bacteria attached to the small intestinal epithelium of some untreated and treated celiac-disease patients, but not to the epithelium of healthy controls, ignites the notion that bacteria may be involved in the pathogenesis of celiac disease. This editorial discusses this possibility in relation to the current understanding of the molecular basis of this disorder.

Publication types

  • Comment
  • Comparative Study
  • Editorial

MeSH terms

  • Adolescent
  • Celiac Disease / immunology*
  • Celiac Disease / microbiology*
  • Child
  • Child, Preschool
  • Colony Count, Microbial
  • Culture Techniques
  • Female
  • Gram-Negative Bacteria / isolation & purification
  • Gram-Positive Bacteria / isolation & purification
  • Humans
  • Immunity, Innate / physiology*
  • Infant
  • Intestinal Mucosa / immunology
  • Intestinal Mucosa / microbiology
  • Male
  • Sensitivity and Specificity