Concurrent benign teratoid medulloepithelioma and pineoblastoma

Ophthalmic Surg. 1992 Jun;23(6):403-8.


Teratoid medulloepithelioma of the ciliary body is a rare tumor usually occurring in young children. Primary tumors of the pineal gland are also quite rare and have a similar age distribution. We report the case of a 2-year-old girl who had a leukocoria of the right eye. Cataract surgery was performed; however, the patient developed a total retinal detachment refractory to treatment. She eventually developed early changes of phthisis bulbi and underwent an evisceration. Histopathologic examination revealed a benign teratoid medulloepithelioma containing islands of hyaline cartilage and rhabdomyoblasts. During the course of her evaluation, a pineoblastoma was discovered and surgically excised. While the association of pineal tumors with retinoblastomas has been well established, no such association has been reported for medulloepitheliomas. To our knowledge, this is the first recorded case of a benign teratoid medulloepithelioma occurring concurrently with a pineoblastoma.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Brain Neoplasms / diagnostic imaging
  • Brain Neoplasms / pathology*
  • Child, Preschool
  • Ciliary Body / diagnostic imaging
  • Ciliary Body / pathology*
  • Eye Enucleation
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Neoplasms, Multiple Primary*
  • Neuroectodermal Tumors, Primitive, Peripheral / diagnostic imaging
  • Neuroectodermal Tumors, Primitive, Peripheral / pathology*
  • Pinealoma / diagnostic imaging
  • Pinealoma / pathology*
  • Teratoma / diagnostic imaging
  • Teratoma / pathology*
  • Tomography, X-Ray Computed
  • Uveal Neoplasms / diagnostic imaging
  • Uveal Neoplasms / pathology*