Propionic acidemia and zinc deficiency presenting as necrolytic migratory erythema

Saudi Med J. 2004 May;25(5):660-2.

Abstract

Necrolytic migratory erythema was first described in 1942 in a patient with pancreatic islet cell carcinoma. The disease can, however, have other etiologies including nutritional dermatoses. Here, we describe the clinicopathological picture of a 7-year-old female patient who presented with necrolytic migratory erythema which we believe is secondary to a rare combination of zinc deficiency and propionic acidemia.

Publication types

  • Case Reports

MeSH terms

  • Acrodermatitis / etiology*
  • Acrodermatitis / pathology
  • Biopsy
  • Child
  • Diagnosis, Differential
  • Erythema / etiology*
  • Erythema / pathology
  • Female
  • Humans
  • Necrosis
  • Propionates / blood*
  • Skin / pathology
  • Skin Diseases, Metabolic / diagnosis*
  • Skin Diseases, Metabolic / pathology
  • Stevens-Johnson Syndrome / diagnosis*
  • Stevens-Johnson Syndrome / pathology
  • Zinc / deficiency*

Substances

  • Propionates
  • Zinc
  • propionic acid