[Diabetes-associated autoimmune disease in children and juveniles: how important is early recognition?]

Dtsch Med Wochenschr. 2004 May 14;129(20):1145-8. doi: 10.1055/s-2004-824863.
[Article in German]

Abstract

Coeliac disease (CD) and autoimmune thyreoiditis (AIT) are associated with type-1 diabetes. These diseases frequently occur without apparent clinical symptoms. Therefore, a serological screening by autoantibody testing is required for early detection. Identified by screening, the prevalence of CD and AIT is reported to be up to 10-fold higher in young patients with type-1 diabetes than in healthy children. Up to now, no uniform recommendations exist regarding a standardized screening procedure as well as the treatment of patients with clinically asymptomatic disorder and evidence of autoimmunity. A delay in the detection of associated diseases, however, may lead to clinical relevant, but otherwise preventable complications.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Adolescent
  • Autoantibodies / blood
  • Celiac Disease / diagnosis*
  • Celiac Disease / etiology
  • Child
  • Diabetes Mellitus, Type 1 / complications*
  • Humans
  • Risk Factors
  • Thyroiditis, Autoimmune / diagnosis*
  • Thyroiditis, Autoimmune / etiology

Substances

  • Autoantibodies