From knowledge to practice in chronic cardiovascular disease: a long and winding road

J Am Coll Cardiol. 2004 May 19;43(10):1738-42. doi: 10.1016/j.jacc.2003.12.043.


Although clinical practices evolve over time, the translation of specific research evidence into clinical practice is unpredictable, inconsistent, and complex. In this paper, we use examples from chronic cardiovascular conditions to: 1). highlight two types of care gaps; 2). describe the most common potential barriers to the application of evidence into clinical care; and 3). outline which of the strategies for translating evidence into clinical care have been shown to be ineffective, which strategies have been shown to be effective and to describe some untested approaches that hold promise.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cardiovascular Diseases / diagnosis
  • Cardiovascular Diseases / physiopathology
  • Cardiovascular Diseases / therapy*
  • Chronic Disease
  • Delivery of Health Care / standards*
  • Evidence-Based Medicine
  • Humans
  • Patient Care / methods
  • Professional Practice / standards*
  • Quality of Health Care / standards