Percutaneous vertebroplasty: history, technique and current perspectives

Clin Radiol. 2004 Jun;59(6):461-7. doi: 10.1016/j.crad.2004.01.001.


Percutaneous vertebroplasty is a safe and efficacious technique for the treatment of persistent pain from a fractured vertebral body. Injection of cement into the vertebral body is made after insertion of a large-bore needle, frequently by a trans-pedicular approach. Vertebroplasty is most commonly used to treat painful osteoporotic fracture resistant to conservative therapy, but may be helpful in other conditions such as malignant collapse. NICE guidelines are now available for this procedure, which is relatively new in the UK, but has been performed for more than 15 years in continental Europe.

Publication types

  • Review

MeSH terms

  • Bone Cements / therapeutic use*
  • Humans
  • Injections, Spinal
  • Osteoporosis / complications
  • Pain / prevention & control*
  • Polymethyl Methacrylate / administration & dosage*
  • Risk Factors
  • Spinal Fractures / diagnostic imaging
  • Spinal Fractures / therapy*
  • Tomography, X-Ray Computed / methods


  • Bone Cements
  • Polymethyl Methacrylate