Dendritic cell, the immunotherapeutic cell for cancer

Indian J Med Res. 2004 Apr;119(4):133-8.


Dendritic cells play an important role in the development of effective cancer vaccines. These cells have the potential to present tumour-specific antigens and thereby induce an immune response. Various studies involving clinical trials have investigated the efficacy of administering antigen-loaded dendritic cells for cancer therapy. In order to design such experiments it is important to consider specific antigens, which initiate either a CD4+ or CD8+ response or both. The present review discusses the unique properties of dendritic cells as an immunotherapeutic cell for cancer.

Publication types

  • Review

MeSH terms

  • Antigens, Neoplasm / chemistry
  • CD4-Positive T-Lymphocytes / metabolism
  • CD8-Positive T-Lymphocytes / metabolism
  • Clinical Trials as Topic
  • Dendritic Cells / cytology*
  • Dendritic Cells / immunology
  • Humans
  • Immunotherapy / methods*
  • Neoplasms / therapy*
  • Peptides / chemistry
  • Transfection
  • Vaccines / chemistry


  • Antigens, Neoplasm
  • Peptides
  • Vaccines