MRI of five patients with mitochondrial neurogastrointestinal encephalomyopathy

AJR Am J Roentgenol. 2004 Jun;182(6):1537-41. doi: 10.2214/ajr.182.6.1821537.


Objective: The purpose of this study was to retrospectively review MR images of the brain in five patients diagnosed with mitochondrial neurogastrointestinal encephalomyopathy.

Conclusion: Our research supports previously reported findings of confluent abnormal cerebral white matter in patients with mitochondrial neurogastrointestinal encephalomyopathy. In contrast to prior studies, our cohort of five patients showed that involvement of the corpus callosum as well as the capsular white matter, basal ganglia, thalami, midbrain, pons, and cerebellar white matter is not rare and does not preclude the diagnosis of mitochondrial neurogastrointestinal encephalomyopathy.

MeSH terms

  • Adult
  • Female
  • Gastrointestinal Diseases / complications
  • Gastrointestinal Diseases / diagnosis*
  • Humans
  • Incidence
  • Magnetic Resonance Imaging*
  • Male
  • Middle Aged
  • Mitochondrial Encephalomyopathies / complications
  • Mitochondrial Encephalomyopathies / diagnosis*
  • Retrospective Studies
  • Severity of Illness Index