Swiss-Prot: juggling between evolution and stability

Brief Bioinform. 2004 Mar;5(1):39-55. doi: 10.1093/bib/5.1.39.


We describe some of the aspects of Swiss-Prot that make it unique, explain what are the developments we believe to be necessary for the database to continue to play its role as a focal point of protein knowledge, and provide advice pertinent to the development of high-quality knowledge resources on one aspect or the other of the life sciences.

Publication types

  • Historical Article
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Databases, Protein* / history
  • History, 20th Century
  • History, 21st Century
  • Humans
  • Information Storage and Retrieval
  • Internet
  • Proteins / classification
  • Proteins / genetics
  • Software Design*
  • User-Computer Interface


  • Proteins