Mortality in DSM-IIIR schizophrenia

Schizophr Res. 1992 Jul;7(2):109-16. doi: 10.1016/0920-9964(92)90040-c.


Mortality was investigated in 356 DSM-IIIR schizophrenics admitted to a university psychiatric hospital over a 12-year period. Determination of death was made through a record-linkage process and observed death was compared with the mortality experience of the general population of the State of Iowa. Schizophrenics had nearly a three-fold increase in overall mortality. Mortality was primarily attributable to unnatural causes of death, particularly suicide, which was more than twenty-three times greater than expected. Mortality was greater in schizophrenic patients younger than 40 years and during the early portion of follow-up. Studies of mortality in psychiatric patients continue to be important, particularly as diagnostic criteria become better refined.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Aged
  • Cause of Death*
  • Female
  • Follow-Up Studies
  • Humans
  • Iowa / epidemiology
  • Male
  • Middle Aged
  • Psychiatric Status Rating Scales*
  • Risk Factors
  • Schizophrenia / diagnosis
  • Schizophrenia / mortality*
  • Schizophrenic Psychology*