Acute brain injury in hypoglycaemia-induced hemiplegia

Diabet Med. 2004 Jun;21(6):623-4. doi: 10.1111/j.1464-5491.2004.01185.x.


Background: The development of hemiplegia as a result of hypoglycaemia was first described in 1928. However, the mechanism remains unclear.

Case report: We report a case of a 58-year-old male with diabetes, who developed left hemiplegia during a severe hypoglycaemic event. Results Diffusion-weighted magnetic resonance imaging detected an increased signal intensity in the pons, indicating that the patient's hemiplegia resulted from acute brain injury.

Conclusions: This report provides evidence that acute brain injury may be a cause of the neurological deficit.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Brain Injuries / complications*
  • Diabetes Mellitus, Type 2 / complications*
  • Diabetes Mellitus, Type 2 / drug therapy
  • Hemiplegia / etiology*
  • Humans
  • Hypoglycemia / complications*
  • Insulin / poisoning
  • Magnetic Resonance Imaging / methods
  • Male
  • Middle Aged
  • Suicide, Attempted


  • Insulin