Neuropeptide Y-like immunoreactive neurons in the suprachiasmatic-subparaventricular region in the hedgehog-tenrec

Brain Res. 1992 Apr 3;576(2):332-6. doi: 10.1016/0006-8993(92)90699-a.


The distribution of the neuropeptide Y (NPY) was studied in geniculate and peri-chiasmatic regions in the lesser hedgehog-tenrec, Echinops telfairi (Insectivora). Only few neurons demonstrated NPY-like immunoreactivity in the ventral lateral geniculate nucleus. In contrast, NPY-immunoreactive perikarya were clearly present in the suprachiasmatic nucleus (SCh) and dorsal and caudal to it. The latter region might correspond to the subparaventricular zone (SPV), recently identified in the rat as an additional area involved in processing circadian rhythms. While the distribution of a distinct cell population across nuclear boundries in both SCh and SPV might conform to the present idea of processing circadian rhythms, the presence of NPY-like immunoreactive neurons in these areas is rather unusual. In mammals, such neurons have only been demonstrated so far in the mentioned insectivore as well as in man.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Circadian Rhythm
  • Female
  • Hedgehogs / anatomy & histology*
  • Male
  • Nerve Fibers / ultrastructure
  • Neurons / cytology*
  • Neuropeptide Y / analysis*
  • Paraventricular Hypothalamic Nucleus / anatomy & histology
  • Paraventricular Hypothalamic Nucleus / cytology*
  • Suprachiasmatic Nucleus / anatomy & histology
  • Suprachiasmatic Nucleus / cytology*


  • Neuropeptide Y