Antibacterial activity of coriander volatile compounds against Salmonella choleraesuis

J Agric Food Chem. 2004 Jun 2;52(11):3329-32. doi: 10.1021/jf0354186.


Aliphatic (2E)-alkenals and alkanals characterized from the fresh leaves of the coriander Coriandrum sativum L. (Umbelliferae) were found to possess bactericidal activity against Salmonella choleraesuis ssp. choleraesuis ATCC 35640. (2E)-Dodecenal (C(12)) was the most effective against this food-borne bacterium with the minimum bactericidal concentration (MBC) of 6.25 microg/mL (34 microM), followed by (2E)-undecenal (C(11)) with an MBC of 12.5 microg/mL (74 microM). The time-kill curve study showed that these alpha,beta-unsaturated aldehydes are bactericidal against S. choleraesuis at any growth stage and that their bactericidal action comes in part from the ability to act as nonionic surfactants.

MeSH terms

  • Aldehydes / pharmacology*
  • Alkanes / pharmacology*
  • Alkenes / pharmacology*
  • Anti-Bacterial Agents / pharmacokinetics*
  • Coriandrum / chemistry*
  • Salmonella / drug effects*
  • Volatilization


  • Aldehydes
  • Alkanes
  • Alkenes
  • Anti-Bacterial Agents