Correlations between family history and cancer characteristics in 2256 breast cancer patients

Br J Cancer. 2004 Jul 5;91(1):96-8. doi: 10.1038/sj.bjc.6601905.


A comparison of 692 early invasive breast cancer with, and 1564 without, a family history of breast cancer showed that the former were younger at diagnosis (P=0.002), had smaller tumours (P=0.012), were more frequently oestrogen receptor positive (P=0.006) and diagnosed preclinically (P<0.001).

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Age of Onset
  • Aged
  • Aged, 80 and over
  • Breast Neoplasms / genetics*
  • Breast Neoplasms / pathology*
  • Case-Control Studies
  • Female
  • Genetic Predisposition to Disease*
  • Humans
  • Middle Aged
  • Neoplasm Staging
  • Receptors, Estrogen / analysis


  • Receptors, Estrogen