Frontal lobe seizures and uveitis associated with acute human parvovirus B19 infection

J Child Neurol. 2004 Apr;19(4):304-6. doi: 10.1177/088307380401900413.

Abstract

We report a 5-year-old girl who developed repeated episodes of behavioral alterations shortly after human parvovirus B19 infection and uveitis. Video-electroencephalographic study demonstrated that these brief episodes were frontal lobe seizures. Seizures responded promptly to antiepilepsy medications. Further diagnostic testing did not reveal any rheumatologic disorders. Human parvovirus B19 infections in children are more commonly associated with febrile seizures and meningoencephalitis. Our case demonstrates that, rarely, it may be associated with the development of partial epilepsy.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Anti-Inflammatory Agents / therapeutic use
  • Anticonvulsants / therapeutic use
  • Brain / pathology
  • Carbamazepine / therapeutic use
  • Child, Preschool
  • Electroencephalography
  • Erythema Infectiosum / complications
  • Erythema Infectiosum / diagnosis*
  • Erythema Infectiosum / drug therapy
  • Erythema Infectiosum / virology
  • Female
  • Frontal Lobe / physiopathology*
  • Humans
  • Lamotrigine
  • Magnetic Resonance Imaging
  • Ophthalmic Solutions
  • Parvovirus B19, Human* / isolation & purification
  • Phenytoin / analogs & derivatives*
  • Phenytoin / therapeutic use
  • Polymerase Chain Reaction
  • Prednisone / therapeutic use
  • Seizures / complications
  • Seizures / drug therapy
  • Seizures / virology*
  • Triazines / therapeutic use
  • Uveitis / complications
  • Uveitis / drug therapy
  • Uveitis / virology*
  • Video Recording

Substances

  • Anti-Inflammatory Agents
  • Anticonvulsants
  • Ophthalmic Solutions
  • Triazines
  • Carbamazepine
  • Phenytoin
  • fosphenytoin
  • Lamotrigine
  • Prednisone