A medicinal chemistry perspective on artemisinin and related endoperoxides

J Med Chem. 2004 Jun 3;47(12):2945-64. doi: 10.1021/jm030571c.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Alkylation
  • Antimalarials / chemistry
  • Antimalarials / pharmacology*
  • Antimalarials / therapeutic use
  • Artemisinins / chemistry
  • Artemisinins / pharmacology*
  • Artemisinins / therapeutic use
  • Cysteine Proteinase Inhibitors / chemistry
  • Cysteine Proteinase Inhibitors / therapeutic use
  • Drug Resistance
  • Drug Stability
  • Drug Therapy, Combination
  • Heme / metabolism
  • Humans
  • Malaria, Falciparum / drug therapy
  • Oxidative Stress
  • Prodrugs / chemistry
  • Prodrugs / therapeutic use
  • Sesquiterpenes / chemistry
  • Sesquiterpenes / pharmacology*
  • Sesquiterpenes / therapeutic use

Substances

  • Antimalarials
  • Artemisinins
  • Cysteine Proteinase Inhibitors
  • Prodrugs
  • Sesquiterpenes
  • Heme
  • artemisinin