Quality assessment of the human genome sequence

Nature. 2004 May 27;429(6990):365-8. doi: 10.1038/nature02390.


As the final sequencing of the human genome has now been completed, we present the results of the largest examination of the quality of the finished DNA sequence. The completed study covers the major contributing sequencing centres and is based on a rigorous combination of laboratory experiments and computational analysis.

Publication types

  • Multicenter Study

MeSH terms

  • Base Pairing
  • Computational Biology / standards*
  • Computational Biology / trends
  • Genome, Human*
  • Human Genome Project*
  • Humans
  • Quality Control
  • Research Design
  • Sensitivity and Specificity
  • Sequence Analysis, DNA / standards*
  • Sequence Analysis, DNA / trends