Occupational exposure to diesel and gasoline engine exhausts and risk of lung cancer among Finnish workers

Am J Ind Med. 2004 Jun;45(6):483-90. doi: 10.1002/ajim.20013.


Background: Studies on engine exhausts and lung cancer have given inconsistent results.

Methods: Economically active Finns were followed-up for lung cancer during 1971-95 (33,664 cases). Their Census occupations in 1970 were converted to exposures to diesel and gasoline engine exhausts with a job-exposure matrix. The relative risks (RRs) for cumulative exposure (CE) were defined by Poisson regression, adjusted for smoking, asbestos, and quartz dust exposure, and socioeconomic status.

Results: RR for engine exhausts among men did not increase with increasing CE. In women, RR for gasoline engine exhaust was 1.58 (95% CI 1.10-2.26) in the CE-category of 1-99 mg/m(3)-y and 1.66 (1.11-2.50) among those with > or =100 mg/m(3)-y (lag 20 years). With a lag of 10 years RR for the middle/highest diesel exhaust category in women was 1.42 (0.94-2.13).

Conclusions: Occupational exposure to engine exhausts was not consistently associated with lung cancer in this study, possibly due to low exposure levels.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Female
  • Finland / epidemiology
  • Humans
  • Lung Neoplasms / epidemiology
  • Lung Neoplasms / etiology*
  • Male
  • Middle Aged
  • Occupational Exposure*
  • Occupations
  • Poisson Distribution
  • Registries / statistics & numerical data
  • Risk Assessment
  • Risk Factors
  • Vehicle Emissions / toxicity*


  • Vehicle Emissions