Treatment of rheumatoid arthritis with etanercept

Rheum Dis Clin North Am. 2004 May;30(2):311-28, vi-vii. doi: 10.1016/j.rdc.2004.01.004.


Etanercept is effective in the treatment of rheumatoid arthritis (RA)when used as monotherapy and in combination with methotrexate(MTX). Radiographic progression of disease was slowed significantly when the drug was used for a 24-month period and was statistically significantly better than MTX. In addition to its use in RA,etanercept is approved by the U.S. Food and Drug Administration for other rheumatologic conditions, including psoriatic arthritis,ankylosing spondylitis, and juvenile chronic arthritis.

Publication types

  • Review

MeSH terms

  • Antirheumatic Agents / adverse effects
  • Antirheumatic Agents / pharmacology
  • Antirheumatic Agents / therapeutic use*
  • Arthritis / drug therapy
  • Arthritis, Rheumatoid / drug therapy*
  • Etanercept
  • Granulomatosis with Polyangiitis / drug therapy
  • Humans
  • Immunoglobulin G / adverse effects
  • Immunoglobulin G / pharmacology
  • Immunoglobulin G / therapeutic use*
  • Receptors, Tumor Necrosis Factor / therapeutic use*


  • Antirheumatic Agents
  • Immunoglobulin G
  • Receptors, Tumor Necrosis Factor
  • Etanercept