Sleep and quantitative EEG in neurodegenerative disorders

J Psychosom Res. 2004 May;56(5):487-96. doi: 10.1016/j.jpsychores.2004.02.001.


This paper reviews current knowledge on sleep problems, sleep architecture changes and quantitative EEG alteration brought on by various neurodegenerative diseases, such as Alzheimer's disease (AD), progressive supranuclear palsy (PSP), REM sleep behavior disorder (RBD), Parkinson's disease (PD), dementia with Lewy bodies (DLB), multiple system atrophy MSA, Huntington's disease and Creutzfeldt-Jakob disease, in comparison to normal aging. The study of sleep variables and that of the spectral composition of the EEG can provide valuable information for understanding the pathophysiology and for assisting the diagnosis of neurodegenerative diseases.

Publication types

  • Review

MeSH terms

  • Aged
  • Aging / physiology*
  • Electroencephalography
  • Humans
  • Middle Aged
  • Neurodegenerative Diseases / complications*
  • Sleep Wake Disorders / physiopathology*