PROBIT: weighted probit regression analysis for estimation of biological activity

J Immunol Methods. 1992 Aug 30;153(1-2):261-2. doi: 10.1016/0022-1759(92)90329-r.


PROBIT estimates biologic activity by weighted probit regression analysis and comparison with a known standard. The program is intended to speed up calculation of the concentration of cytokines in large numbers of cell supernatants. Data are input from either sequential or free-form text files created with a spreadsheet or text editor. This allows transfer of data from a beta-counter equipped with a suitable terminal without retyping. Results are displayed and/or printed as relative potency (% of standard) and 50% effective dose (ED50).

MeSH terms

  • Cytokines / analysis*
  • Regression Analysis
  • Software*


  • Cytokines