Palladium-catalyzed decarboxylation and decarbonylation under hydrothermal conditions: decarboxylative deuteration

Seijiro Matsubara; Yutaka Yokota; Koichiro Oshima

doi:10.1021/ol0492602

Palladium-catalyzed decarboxylation and decarbonylation under hydrothermal conditions: decarboxylative deuteration

Org Lett. 2004 Jun 10;6(12):2071-3. doi: 10.1021/ol0492602.

Authors

Seijiro Matsubara¹, Yutaka Yokota, Koichiro Oshima

Affiliation

¹ Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoudai-katsura, Nishikyo, Kyoto 615-8510, Japan. matsubar@orgrxn.mbox.media.kyoto-u.ac.jp

PMID: 15176821
DOI: 10.1021/ol0492602

Abstract

[reaction: see text] Decarboxylation of free carboxylic acid was performed by Pd/C catalyst under hydrothermal water (250 degrees C/4 MPa). Under the hydrothermal conditions of deuterium oxide, decarbonylative deuteration was observed to give fully deuterated hydrocarbons from carboxylic acids or aldehydes.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Carbon / chemistry
Catalysis
Decarboxylation
Deuterium Oxide / chemistry
Molecular Structure
Palladium / chemistry*
Temperature*
Time Factors

Substances

Palladium
Carbon
Deuterium Oxide