Stevisalioside A, a novel bitter-tasting ent-atisene glycoside from the roots of Stevia salicifolia

J Nat Prod. 1992 May;55(5):660-6. doi: 10.1021/np50083a017.

Abstract

A new acetylated ent-atisene glycoside, stevisalioside A [1], has been isolated as a bitter-tasting principle from Stevia salicifolia roots. The structure was established by the interpretation of spectral data, with the nmr assignments of this compound being based on 1H-1H COSY, 1H-13C HETCOR, and selective INEPT experiments. A rearrangement product 4 of the aglycone moiety obtained by alkaline hydrolysis supported the structure of 1. This is the first report of the occurrence of an atisane-type diterpene from the genus Stevia.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Carbohydrate Sequence
  • Glycosides / chemistry
  • Glycosides / isolation & purification*
  • Glycosides / metabolism
  • Magnetic Resonance Spectroscopy
  • Molecular Sequence Data
  • Molecular Structure
  • Plants, Medicinal / chemistry*
  • Taste
  • Triterpenes / chemistry
  • Triterpenes / isolation & purification*
  • Triterpenes / metabolism

Substances

  • Glycosides
  • Triterpenes
  • stevisalioside A