The multiparametric scanning system for evaluation of minimal residual disease in hematological malignancies

Acta Haematol. 2004;112(1-2):24-9. doi: 10.1159/000077556.


Combined simultaneous analysis of morphology, immunophenotyping and fluorescence in situ hybridization on the same cell offers advantages that may help to disclose the relevance of minimal residual disease (MRD) detection. Morphological analysis of small populations of cells related either to malignancy or recipient-associated markers may improve the accuracy of chimerism and MRD testing and delineate their clinical significance.

Publication types

  • Review

MeSH terms

  • Cell Size
  • Cytodiagnosis / methods*
  • Hematologic Neoplasms / diagnosis
  • Hematologic Neoplasms / pathology*
  • Histocytochemistry
  • Humans
  • Immunophenotyping
  • In Situ Hybridization, Fluorescence
  • Neoplasm, Residual / diagnosis
  • Neoplasm, Residual / pathology