A bandpass filter based on guided-mode resonance effects in a single-layer periodic waveguide is presented. Strong refractive-index modulation is used to support the excitation of a resonance pair in which leaky waveguide mode TE0 is excited by the second diffraction order and TE2 by the first diffraction order. It is shown that one resonance provides a broad low-transmission band, whereas the other supplies the transmission peak through its asymmetrical line shape. A bandpass filter with central wavelength at 1.55 microm is presented to demonstrate this concept.