Abstract
The term "congenital neutropenia" signifies neutropenia that is present at birth. It includes a wide variety of disorders, some transient and others life long. Some varieties of congenital neutropenia are mild, with blood neutrophil concentrations below normal but not low enough to constitute a significant host defense deficiency. Other varieties of congenital neutropenia are characterized by low blood neutrophil concentrations and a predisposition to repeated infections.
Publication types
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Biography
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Historical Article
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Review
MeSH terms
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Acids / urine
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Acyltransferases
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Antimicrobial Cationic Peptides / deficiency
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Cardiomyopathy, Dilated / genetics
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Cathelicidins
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Cell Transformation, Neoplastic / chemically induced
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Glycogen Storage Disease Type I / complications
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Granulocyte Colony-Stimulating Factor / adverse effects
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Granulocyte Colony-Stimulating Factor / therapeutic use
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History, 20th Century
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Humans
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Immune System Diseases / complications
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Infant, Newborn
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Leukocyte Elastase / genetics
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Metabolism, Inborn Errors / complications
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Mutation
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Neutropenia / congenital*
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Neutropenia / etiology
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Neutropenia / history
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Neutropenia / physiopathology
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Proteins / genetics
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Recombinant Proteins / adverse effects
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Recombinant Proteins / therapeutic use
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Sweden
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Syndrome
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Transcription Factors / genetics
Substances
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Acids
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Antimicrobial Cationic Peptides
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Cathelicidins
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Proteins
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Recombinant Proteins
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Transcription Factors
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Granulocyte Colony-Stimulating Factor
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Acyltransferases
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tafazzin protein, mouse
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TAFAZZIN protein, human
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Leukocyte Elastase