Post-surgical scleritis associated with the ganciclovir implant

Ophthalmic Surg Lasers Imaging. 2004 May-Jun;35(3):254-5.


Although the ganciclovir implant is an effective and well-tolerated treatment for cytomegalovirus retinitis in patients with human immunodeficiency virus infection, complications that may occur include retinal detachment, implant extrusion, and endophthalmitis. A 22-year-old woman with human immunodeficiency virus infection presented with a painful left eye with scleritis overlying previous ganciclovir implant sclerotomy sites. The inflammation progressed 360 degrees around the pars plana with progressive thinning at the implant sites. Post-surgical necrotizing scleritis is another complication that can occur in patients with ganciclovir implants.

Publication types

  • Case Reports

MeSH terms

  • AIDS-Related Opportunistic Infections / drug therapy
  • Adult
  • Antiviral Agents / administration & dosage*
  • Cytomegalovirus Retinitis / drug therapy
  • Drug Implants / adverse effects*
  • Female
  • Ganciclovir / administration & dosage*
  • Humans
  • Postoperative Complications*
  • Scleritis / etiology*


  • Antiviral Agents
  • Drug Implants
  • Ganciclovir