Evolutionary genomics: yeasts accelerate beyond BLAST

Curr Biol. 2004 May 25;14(10):R392-4. doi: 10.1016/j.cub.2004.05.015.


Two new genome sequences confirm that a whole genome duplication occurred in an ancestor of Saccharomyces cerevisiae. This left a legacy of about 500 pairs of duplicated genes, many of which contribute to this yeast's ability to ferment glucose anaerobically; a few have been evolving so quickly they retain almost no sequence similarity to each other.

Publication types

  • Review

MeSH terms

  • Base Sequence
  • Databases, Genetic
  • Evolution, Molecular*
  • Gene Order
  • Genes, Duplicate / genetics*
  • Genetic Variation
  • Genome, Fungal*
  • Phylogeny*
  • Polyploidy
  • Saccharomyces cerevisiae / genetics*
  • Sequence Homology