Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
, 117 (6), 699-711

Protein Tyrosine Phosphatases in the Human Genome

Affiliations
Review

Protein Tyrosine Phosphatases in the Human Genome

Andres Alonso et al. Cell.

Abstract

Tyrosine phosphorylation is catalyzed by protein tyrosine kinases, which are represented by 90 genes in the human genome. Here, we present the set of 107 genes in the human genome that encode members of the four protein tyrosine phosphatase (PTP) families. The four families of PTPases, their substrates, structure, function, regulation, and the role of these enzymes in human disease will be discussed.

Similar articles

See all similar articles

Cited by 556 PubMed Central articles

See all "Cited by" articles

MeSH terms

LinkOut - more resources

Feedback