Use of saline chaser in the intravenous administration of contrast material in non-invasive coronary angiography with 16-row multislice Computed Tomography

Radiol Med. 2004 May-Jun;107(5-6):497-505.
[Article in English, Italian]

Abstract

Purpose: To investigate the impact of saline bolus chaser in coronary angiography with a 16-row multislice CT (16-MSCT) scanner.

Materials and methods: 32 patients were divided in two groups for contrast material (cm) administration: group 1 (140 ml at 4 ml/s), and group 2 (100 ml at 4 ml/s followed by 40 ml of saline chaser at 4 ml/s). All patients underwent ECG-gated coronary angiography with a 16-MSCT scanner. The attenuation at the origin coronary vessels was assessed. Three regions of interest were drawn throughout the data-set: ascending aorta (ROI1); descending aorta (ROI2); pulmonary artery (ROI3). The attenuation in the superior vena cava was recorded (ROI4). The average attenuation and the slope were calculated in each ROI.

Results: The average attenuation in the coronary vessels was not significantly different in the two groups. The attenuation value in the superior vena cava was significantly inferior in group 2.

Conclusions: 16-row MSCT coronary angiography with bolus chaser allows optimal vessel enhancement with a lower dose of cm and a lower enhancement of the superior vena cava and the right heart.

Publication types

  • Clinical Trial
  • Comparative Study
  • Controlled Clinical Trial

MeSH terms

  • Adult
  • Aged
  • Contrast Media / administration & dosage*
  • Coronary Angiography / methods*
  • Female
  • Humans
  • Infusions, Intravenous
  • Male
  • Middle Aged
  • Prospective Studies
  • Sodium Chloride / administration & dosage*
  • Tomography, X-Ray Computed* / methods

Substances

  • Contrast Media
  • Sodium Chloride