Ketone deprotonation mediated by mono- and heterobimetallic alkali and alkaline earth metal amide bases: structural characterization of potassium, calcium, and mixed potassium-calcium enolates

Xuyang He; Bruce C Noll; Alicia Beatty; Robert E Mulvey; Kenneth W Henderson

doi:10.1021/ja048750m

Ketone deprotonation mediated by mono- and heterobimetallic alkali and alkaline earth metal amide bases: structural characterization of potassium, calcium, and mixed potassium-calcium enolates

J Am Chem Soc. 2004 Jun 23;126(24):7444-5. doi: 10.1021/ja048750m.

Authors

Xuyang He¹, Bruce C Noll, Alicia Beatty, Robert E Mulvey, Kenneth W Henderson

Affiliation

¹ Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, USA.

PMID: 15198583
DOI: 10.1021/ja048750m

Abstract

Potassium, calcium, and mixed potassium-calcium amide combinations have been shown to be efficient reagents in enolization reactions, and a set of representative intermediate mono- and heterobimetallic enolates have been successfully isolated and crystallographically characterized.