A Randomised Trial of Single-Dose Radiotherapy to Prevent Procedure Tract Metastasis by Malignant Mesothelioma

Br J Cancer. 2004 Jul 5;91(1):9-10. doi: 10.1038/sj.bjc.6601957.

Abstract

A single 9-MeV electron treatment, following invasive thoracic procedures in patients with malignant pleural mesothelioma, was examined. In all, 58 sites were randomised to prophylactic radiotherapy or not. There was no statistically significant difference in tract metastasis. A single 10-Gy treatment with 9-MeV electrons appears ineffective.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Aged
  • Aged, 80 and over
  • Electrons / therapeutic use
  • Female
  • Humans
  • Male
  • Mesothelioma / radiotherapy*
  • Mesothelioma / secondary*
  • Mesothelioma / surgery
  • Middle Aged
  • Neoplasm Metastasis / prevention & control*
  • Neoplastic Cells, Circulating*
  • Pleural Neoplasms / pathology*
  • Pleural Neoplasms / radiotherapy*
  • Pleural Neoplasms / surgery
  • Postoperative Complications / prevention & control*
  • Radiotherapy Dosage
  • Treatment Outcome